For some people trazodone also potently blocks psychedelic effects (undoubtedly via 5ht-2a)
Here's a trazodone story from a mushroom thread. I assume he took far more than Construct's micro dose.
Trazodone and the mCPP metabolite have a long list of affinities. 5-HT2A and a1 antagonism are at the top of the list for Trazodone.
Trazodone is also a 5-HT2B antagonist. There are some studies showing that 5-HT2B antagonism blocks the effects of SSRIs.
I've been having good luck with about 1/10th of a 50mg Trazodone pill at night. If I wake up before 4AM, I nibble off another tiny piece and go back to bed. The dose is so small that I thought it might be placebo, but my sleep is objectively much worse if I don't take it. That 5-HT2A antagonism is potent.