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For the first time, researchers at Northwestern University's Feinberg School of Medicine have identified how a single gene called aromatase (CYP19A1) triggers a chain reaction in the brain that converts testosterone into estrogen and seems to drive sexual desire in male mice. These findings (Brooks et al., 2020) were published on September 10 in the journal Endocrinology. 


Psychology Today Article

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at 2 pumps of T per day, I am rocking ~200ng with .1mg of anastrozole EoD. Maybe I should go E3D.


200 is crap, but I have literally no symptoms at the moment, and when I was at 4 pumps and no AI, my bloating and water retention was high as hell, and my T was ~150-ish. 

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  • 1 month later...


....some time ago when i lost sexual function from nolvadex,

rescuing the stuff (almost)

i have to take some oral estradiol....

not the same thing (localized is much better)(brain)


....but i worked


Localization of testosterone-sensitive and sexually dimorphic aromatase-immunoreactive cells in the quail preoptic area



Steroid control and sexual differentiation of brain aromatase



Rapid Decreases in Preoptic Aromatase Activity and Brain Monoamine Concentrations after Engaging in Male Sexual Behavior




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