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Androgen Steroids with low and high affinity with AR


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I did  this actualized version of division in Androgen Receptor (AR) affinity of Steroids. What you think about?

 

Class 1 and Class 2 Anabolic Steroids:

Of the countless ways that we can divide androgenic anabolic steroids (EAA's), we can divide by their affinity with the Androgenic Receptor (RA). AR is a soluble protein that acts on cell transcription, has nuclear reception activated by androgens (Testosterone and derivatives) in the cell's cytoplasm and moving to the nucleus. He is responsible for male sexual differentiation.


It acts mainly on tissues such as musculoskeletal, prostate, liver and central nervous system (CNS). EAA's act on skeletal muscle tissue by RA or another receptor.

In the following list I will show the updated affinity division with AR:

 

Class 1 steroids (high affinity for AR):

Boldenone (medium affinity)
Chlorodehydromethyltestosterone (Turinabol)
Drostanolone (Masteron)
Mestenolone (Ermalone)
Mesterolone (Proviron)
Methenolone (Primobolan)
Metribolone
Mibolerone
Nandrolone
Normetandrona
Testosterone
Trenbolone

 

Class 2 steroids (low affinity for AR):

Fluoxymesterone (Halotestin)
Methandrostenolone (Dianabol)
Oxandrolone
Oxymetholone (Hemogenin)
Stanozolol

 

This information can help to assemble the disposition of hormones with greater synergy, and predominantly different reception routes. In this way, we will enhance its effect and possibly reduce collateral.

Was there any missing on our list?

 

Sources:
DOI: 10.1210 / endo-114-6-2100
DOI: 10.1007 / 978-90-481-3303-1_6
DOI: 10.1021 / cr020456u

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